| | Lee County | SC | 45061 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=LeeCounty+SC |
| | Lexington County | SC | 45063 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=LexingtonCounty+SC |
| | Marion County | SC | 45067 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=MarionCounty+SC |
| | Marlboro County | SC | 45069 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=MarlboroCounty+SouthCarolina |
| | McCormick County | SC | 45065 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=McCormickCounty+SC |
| | Newberry County | SC | 45071 | | Newberry, SC 35140 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=NewberryCounty+SC |
| | Oconee County | SC | 45073 | | Seneca, SC 42860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=OconeeCounty+SC |
| | Orangeburg County | SC | 45075 | | Orangeburg, SC 36700 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OrangeburgCounty+SC |
| | Pickens County | SC | 45077 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=PickensCounty+SC |
| | Richland County | SC | 45079 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=RichlandCounty+SC |