| | Spartanburg County | SC | 45083 | | Spartanburg, SC 43900 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=SpartanburgCounty+SC |
| | Sumter County | SC | 45085 | | Sumter, SC 44940 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SumterCounty+SC |
| | Abbeville County | SC | 45001 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=AbbevilleCounty+SC |
| | Anderson County | SC | 45007 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=AndersonCounty+SC |
| | Calhoun County | SC | 45017 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=CalhounCounty+SC |
| | Chester County | SC | 45023 | | Charlotte-Concord-Gastonia,
NC-SC 16740 | Charlotte-Concord, NC-SC 172 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=ChesterCounty+SC |
| | Darlington County | SC | 45031 | | Florence, SC 22500 | | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=DarlingtonCounty+SC |
| | Edgefield County | SC | 45037 | | Augusta-Richmond County,
GA-SC 12260 | | Outlying | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=EdgefieldCounty+SC |
| | Fairfield County | SC | 45039 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Outlying | metro county (urban) | nonspecialized | https://maps.google.com/?q=FairfieldCounty+SC |
| | Jasper County | SC | 45053 | | Hilton Head
Island-Bluffton-Port
Royal, SC 25940 | | Outlying | metro county (urban) | nonspecialized | https://maps.google.com/?q=JasperCounty+SC |