| | Roberts County | SD | 46109 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=RobertsCounty+SD |
| | Sanborn County | SD | 46111 | | Mitchell, SD 33580 | | Outlying | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SanbornCounty+SD |
| | Spink County | SD | 46115 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SpinkCounty+SD |
| | Stanley County | SD | 46117 | | Pierre, SD 38180 | | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=StanleyCounty+SD |
| | Sully County | SD | 46119 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SullyCounty+SD |
| | Todd County | SD | 46121 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=ToddCounty+SD |
| | Tripp County | SD | 46123 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=TrippCounty+SD |
| | Turner County | SD | 46125 | | Sioux Falls, SD-MN 43620 | | Outlying | metro county (urban) | farm-dependent | https://maps.google.com/?q=TurnerCounty+SD |
| | Walworth County | SD | 46129 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=WalworthCounty+SD |
| | Yankton County | SD | 46135 | | Yankton, SD 49460 | | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=YanktonCounty+SD |