| | Horry County | SC | 45051 | | Myrtle Beach-Conway-North
Myrtle Beach, SC-NC 34820 | Myrtle Beach-Conway,
SC-NC 396 | Central | metro county (urban) | recreation | https://maps.google.com/?q=HorryCounty+SC |
| | Hampton County | SC | 45049 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=HamptonCounty+SC |
| | Greenwood County | SC | 45047 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=GreenwoodCounty+SC |
| | Greenville County | SC | 45045 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=GreenvilleCounty+SC |
| | Georgetown County | SC | 45043 | | Murrells Inlet, SC 34680 | Myrtle Beach-Conway,
SC-NC 396 | Central | nonmetro county (rural) | recreation | https://maps.google.com/?q=GeorgetownCounty+SouthCarolina |
| | Florence County | SC | 45041 | | Florence, SC 22500 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=FlorenceCounty+SC |
| | Fairfield County | SC | 45039 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Outlying | metro county (urban) | nonspecialized | https://maps.google.com/?q=FairfieldCounty+SC |
| | Edgefield County | SC | 45037 | | Augusta-Richmond County,
GA-SC 12260 | | Outlying | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=EdgefieldCounty+SC |
| | Dorchester County | SC | 45035 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=DorchesterCounty+SC |
| | Dillon County | SC | 45033 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=DillonCounty+SC |