| | Georgetown County | SC | 45043 | | Murrells Inlet, SC 34680 | Myrtle Beach-Conway,
SC-NC 396 | Central | nonmetro county (rural) | recreation | https://maps.google.com/?q=GeorgetownCounty+SouthCarolina |
| | Greenville County | SC | 45045 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=GreenvilleCounty+SC |
| | Greenwood County | SC | 45047 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=GreenwoodCounty+SC |
| | Horry County | SC | 45051 | | Myrtle Beach-Conway-North
Myrtle Beach, SC-NC 34820 | Myrtle Beach-Conway,
SC-NC 396 | Central | metro county (urban) | recreation | https://maps.google.com/?q=HorryCounty+SC |
| | Lexington County | SC | 45063 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=LexingtonCounty+SC |
| | Newberry County | SC | 45071 | | Newberry, SC 35140 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=NewberryCounty+SC |
| | Oconee County | SC | 45073 | | Seneca, SC 42860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=OconeeCounty+SC |
| | Orangeburg County | SC | 45075 | | Orangeburg, SC 36700 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OrangeburgCounty+SC |
| | Pickens County | SC | 45077 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=PickensCounty+SC |
| | Richland County | SC | 45079 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=RichlandCounty+SC |