| | Cherokee County | SC | 45021 | | Gaffney, SC 23500 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=CherokeeCounty+SC |
| | Chesterfield County | SC | 45025 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=ChesterfieldCounty+SC |
| | Clarendon County | SC | 45027 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=ClarendonCounty+SC |
| | Colleton County | SC | 45029 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=ColletonCounty+SC |
| | Dillon County | SC | 45033 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=DillonCounty+SC |
| | Georgetown County | SC | 45043 | | Murrells Inlet, SC 34680 | Myrtle Beach-Conway,
SC-NC 396 | Central | nonmetro county (rural) | recreation | https://maps.google.com/?q=GeorgetownCounty+SouthCarolina |
| | Greenwood County | SC | 45047 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=GreenwoodCounty+SC |
| | Hampton County | SC | 45049 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=HamptonCounty+SC |
| | Lee County | SC | 45061 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=LeeCounty+SC |
| | McCormick County | SC | 45065 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=McCormickCounty+SC |