| | Orangeburg County | SC | 45075 | | Orangeburg, SC 36700 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OrangeburgCounty+SC |
| | Richland County | SC | 45079 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=RichlandCounty+SC |
| | Saluda County | SC | 45081 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=SaludaCounty+SC |
| | Sumter County | SC | 45085 | | Sumter, SC 44940 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SumterCounty+SC |
| | Abbeville County | SC | 45001 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=AbbevilleCounty+SC |
| | Anderson County | SC | 45007 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=AndersonCounty+SC |
| | Cherokee County | SC | 45021 | | Gaffney, SC 23500 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=CherokeeCounty+SC |
| | Greenville County | SC | 45045 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=GreenvilleCounty+SC |
| | Greenwood County | SC | 45047 | | Greenwood, SC 24940 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=GreenwoodCounty+SC |
| | Laurens County | SC | 45059 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=LaurensCounty+SC |