| | Dimmit County | TX | 48127 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=DimmitCounty+TX |
| | Donley County | TX | 48129 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=DonleyCounty+TX |
| | Duval County | TX | 48131 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=DuvalCounty+TX |
| | Eastland County | TX | 48133 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=EastlandCounty+TX |
| | Ector County | TX | 48135 | | Odessa, TX 36220 | Midland-Odessa-Andrews,
TX 372 | Central | metro county (urban) | mining-dependent | https://maps.google.com/?q=EctorCounty+TX |
| | Edwards County | TX | 48137 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=EdwardsCounty+TX |
| | El Paso County | TX | 48141 | | El Paso, TX 21340 | El Paso-Las Cruces, TX-NM 238 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=ElPasoCounty+TX |
| | Erath County | TX | 48143 | | Stephenville, TX 44500 | | Central | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=ErathCounty+TX |
| | Falls County | TX | 48145 | | Waco, TX 47380 | | Outlying | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=FallsCounty+TX |
| | Fannin County | TX | 48147 | | Bonham, TX 14300 | Dallas-Fort Worth, TX-OK 206 | Central | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=FanninCounty+TX |