| | Rusk County | TX | 48401 | | Longview, TX 30980 | | Outlying | metro county (urban) | mining-dependent | https://maps.google.com/?q=RuskCounty+Texas |
| | Sabine County | TX | 48403 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=SabineCounty+TX |
| | San Augustine County | TX | 48405 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=SanAugustineCounty+TX |
| | San Jacinto County | TX | 48407 | | Houston-Pasadena-The
Woodlands, TX 26420 | Houston-Pasadena, TX 288 | Outlying | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=SanJacintoCounty+TX |
| | San Patricio County | TX | 48409 | | Corpus Christi, TX 18580 | Corpus
Christi-Kingsville-Alice,
TX 204 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SanPatricioCounty+TX |
| | San Saba County | TX | 48411 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SanSabaCounty+TX |
| | Schleicher County | TX | 48413 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=SchleicherCounty+TX |
| | Scurry County | TX | 48415 | | Snyder, TX 43660 | | Central | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=ScurryCounty+TX |
| | Shackelford County | TX | 48417 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=ShackelfordCounty+TX |
| | Shelby County | TX | 48419 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=ShelbyCounty+TX |