| | | Marion County | SC | 45067 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=MarionCounty+SC |
| | | Marlboro County | SC | 45069 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=MarlboroCounty+SouthCarolina |
| | | Williamsburg County | SC | 45089 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=WilliamsburgCounty+SC |
| | | Aiken County | SC | 45003 | | Augusta-Richmond County,
GA-SC 12260 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=AikenCounty+SC |
| | | Beaufort County | SC | 45013 | | Hilton Head
Island-Bluffton-Port
Royal, SC 25940 | | Central | metro county (urban) | recreation | https://maps.google.com/?q=BeaufortCounty+SC |
| | | Berkeley County | SC | 45015 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=BerkeleyCounty+SC |
| | | Charleston County | SC | 45019 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=CharlestonCounty+SC |
| | | Cherokee County | SC | 45021 | | Gaffney, SC 23500 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=CherokeeCounty+SC |
| | | Dorchester County | SC | 45035 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=DorchesterCounty+SC |
| | | Florence County | SC | 45041 | | Florence, SC 22500 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=FlorenceCounty+SC |
