| | Leslie County | KY | 21131 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=LeslieCounty+KY |
| | Letcher County | KY | 21133 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=LetcherCounty+KY |
| | Lewis County | KY | 21135 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=LewisCounty+KY |
| | Lincoln County | KY | 21137 | | Danville, KY 19220 | | Outlying | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=LincolnCounty+KY |
| | Logan County | KY | 21141 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=LoganCounty+KY |
| | Lyon County | KY | 21143 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=LyonCounty+KY |
| | McCreary County | KY | 21147 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=McCrearyCounty+KY |
| | McLean County | KY | 21149 | | Owensboro, KY 36980 | | Outlying | metro county (urban) | farm-dependent | https://maps.google.com/?q=McLeanCounty+KY |
| | Magoffin County | KY | 21153 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=MagoffinCounty+KY |
| | Marion County | KY | 21155 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=MarionCounty+KY |