| | Owen County | KY | 21187 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=OwenCounty+KY |
| | Owsley County | KY | 21189 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OwsleyCounty+KY |
| | Perry County | KY | 21193 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=PerryCounty+KY |
| | Powell County | KY | 21197 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=PowellCounty+KY |
| | Robertson County | KY | 21201 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=RobertsonCounty+KY |
| | Rowan County | KY | 21205 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=RowanCounty+KY |
| | Russell County | KY | 21207 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=RussellCounty+KY |
| | Todd County | KY | 21219 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=ToddCounty+KY |
| | Trimble County | KY | 21223 | | | | | metro county (urban) | farm-dependent | https://maps.google.com/?q=TrimbleCounty+KY |
| | Union County | KY | 21225 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=UnionCounty+KY |