| | | Starr County | TX | 48427 | | Rio Grande City-Roma, TX 40100 | McAllen-Edinburg, TX 365 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=StarrCounty+TX |
| | | Somervell County | TX | 48425 | | | | | metro county (urban) | nonspecialized | https://maps.google.com/?q=SomervellCounty+TX |
| | | Smith County | TX | 48423 | | Tyler, TX 46340 | Tyler-Jacksonville, TX 540 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SmithCounty+TX |
| | | Sherman County | TX | 48421 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=ShermanCounty+TX |
| | | Shelby County | TX | 48419 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=ShelbyCounty+TX |
| | | Shackelford County | TX | 48417 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=ShackelfordCounty+TX |
| | | Scurry County | TX | 48415 | | Snyder, TX 43660 | | Central | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=ScurryCounty+TX |
| | | Schleicher County | TX | 48413 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=SchleicherCounty+TX |
| | | San Saba County | TX | 48411 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SanSabaCounty+TX |
| | | San Patricio County | TX | 48409 | | Corpus Christi, TX 18580 | Corpus
Christi-Kingsville-Alice,
TX 204 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SanPatricioCounty+TX |
