| | Scott County | IN | 18143 | | | | | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=ScottCounty+IN |
| | Shelby County | IN | 18145 | | Indianapolis-Carmel-Greenwood,
IN 26900 | Indianapolis-Carmel-Muncie,
IN 294 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=ShelbyCounty+IN |
| | Spencer County | IN | 18147 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=SpencerCounty+IN |
| | St. Joseph County | IN | 18141 | | South Bend-Mishawaka,
IN-MI 43780 | South
Bend-Elkhart-Mishawaka,
IN-MI 515 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=St.JosephCounty+IN |
| | Starke County | IN | 18149 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=StarkeCounty+IN |
| | Steuben County | IN | 18151 | | Angola, IN 11420 | Fort
Wayne-Huntington-Auburn,
IN 258 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=SteubenCounty+IN |
| | Sullivan County | IN | 18153 | | Terre Haute, IN 45460 | | Outlying | metro county (urban) | mining-dependent | https://maps.google.com/?q=SullivanCounty+IN |
| | Switzerland County | IN | 18155 | | | | | nonmetro county (rural) | recreation | https://maps.google.com/?q=SwitzerlandCounty+IN |
| | Tippecanoe County | IN | 18157 | | Lafayette-West Lafayette,
IN 29200 | Lafayette-West
Lafayette-Frankfort, IN 320 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=TippecanoeCounty+IN |
| | Tipton County | IN | 18159 | | Indianapolis-Carmel-Greenwood,
IN 26900 | Indianapolis-Carmel-Muncie,
IN 294 | Outlying | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=TiptonCounty+IN |