| | Ziebach County | SD | 46137 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=ZiebachCounty+SD |
| | Yankton County | SD | 46135 | | Yankton, SD 49460 | | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=YanktonCounty+SD |
| | Walworth County | SD | 46129 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=WalworthCounty+SD |
| | Union County | SD | 46127 | | Sioux City, IA-NE-SD 43580 | Sioux City-Le Mars,
IA-NE-SD 512 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=UnionCounty+SD |
| | Turner County | SD | 46125 | | Sioux Falls, SD-MN 43620 | | Outlying | metro county (urban) | farm-dependent | https://maps.google.com/?q=TurnerCounty+SD |
| | Tripp County | SD | 46123 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=TrippCounty+SD |
| | Todd County | SD | 46121 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=ToddCounty+SD |
| | Sully County | SD | 46119 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SullyCounty+SD |
| | Stanley County | SD | 46117 | | Pierre, SD 38180 | | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=StanleyCounty+SD |
| | Spink County | SD | 46115 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=SpinkCounty+SD |