| | Aiken County | SC | 45003 | | Augusta-Richmond County,
GA-SC 12260 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=AikenCounty+SC |
| | Allendale County | SC | 45005 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=AllendaleCounty+SC |
| | Bamberg County | SC | 45009 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=BambergCounty+SC |
| | Barnwell County | SC | 45011 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=BarnwellCounty+SC |
| | Beaufort County | SC | 45013 | | Hilton Head
Island-Bluffton-Port
Royal, SC 25940 | | Central | metro county (urban) | recreation | https://maps.google.com/?q=BeaufortCounty+SC |
| | Berkeley County | SC | 45015 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=BerkeleyCounty+SC |
| | Charleston County | SC | 45019 | | Charleston-North
Charleston, SC 16700 | | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=CharlestonCounty+SC |
| | Chesterfield County | SC | 45025 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=ChesterfieldCounty+SC |
| | Clarendon County | SC | 45027 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=ClarendonCounty+SC |
| | Colleton County | SC | 45029 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=ColletonCounty+SC |