| | | York County | SC | 45091 | | Charlotte-Concord-Gastonia,
NC-SC 16740 | Charlotte-Concord, NC-SC 172 | Outlying | metro county (urban) | nonspecialized | https://maps.google.com/?q=YorkCounty+SC |
| | | Williamsburg County | SC | 45089 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=WilliamsburgCounty+SC |
| | | Union County | SC | 45087 | | Spartanburg, SC 43900 | Greenville-Spartanburg-Anderson,
SC 273 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=UnionCounty+SC |
| | | Sumter County | SC | 45085 | | Sumter, SC 44940 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=SumterCounty+SC |
| | | Spartanburg County | SC | 45083 | | Spartanburg, SC 43900 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=SpartanburgCounty+SC |
| | | Saluda County | SC | 45081 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Outlying | metro county (urban) | manufacturing-dependent | https://maps.google.com/?q=SaludaCounty+SC |
| | | Richland County | SC | 45079 | | Columbia, SC 17900 | Columbia-Sumter-Orangeburg,
SC 192 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=RichlandCounty+SC |
| | | Pickens County | SC | 45077 | | Greenville-Anderson-Greer,
SC 24860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | metro county (urban) | federal/state
government-dependent | https://maps.google.com/?q=PickensCounty+SC |
| | | Orangeburg County | SC | 45075 | | Orangeburg, SC 36700 | Columbia-Sumter-Orangeburg,
SC 192 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OrangeburgCounty+SC |
| | | Oconee County | SC | 45073 | | Seneca, SC 42860 | Greenville-Spartanburg-Anderson,
SC 273 | Central | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=OconeeCounty+SC |
