| | Nicholas County | KY | 21181 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=NicholasCounty+KY |
| | Ohio County | KY | 21183 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=OhioCounty+KY |
| | Oldham County | KY | 21185 | | Louisville/Jefferson
County, KY-IN 31140 | Louisville/Jefferson
County--Elizabethtown,
KY-IN 350 | Central | metro county (urban) | nonspecialized | https://maps.google.com/?q=OldhamCounty+KY |
| | Owen County | KY | 21187 | | | | | nonmetro county (rural) | farm-dependent | https://maps.google.com/?q=OwenCounty+KY |
| | Owsley County | KY | 21189 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=OwsleyCounty+KY |
| | Pendleton County | KY | 21191 | | Cincinnati, OH-KY-IN 17140 | Cincinnati-Wilmington,
OH-KY-IN 178 | Outlying | metro county (urban) | mining-dependent | https://maps.google.com/?q=PendletonCounty+KY |
| | Perry County | KY | 21193 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=PerryCounty+KY |
| | Pike County | KY | 21195 | | Pikeville, KY 38210 | | Central | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=PikeCounty+KY |
| | Powell County | KY | 21197 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=PowellCounty+KY |
| | Pulaski County | KY | 21199 | | Somerset, KY 43700 | | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=PulaskiCounty+KY |