| | Logan County | KY | 21141 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=LoganCounty+KY |
| | Lyon County | KY | 21143 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=LyonCounty+KY |
| | Madison County | KY | 21151 | | Richmond-Berea, KY 40080 | Lexington-Fayette--Richmond--Frankfort,
KY 336 | Central | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=MadisonCounty+KY |
| | Magoffin County | KY | 21153 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=MagoffinCounty+KY |
| | Marion County | KY | 21155 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=MarionCounty+KY |
| | Marshall County | KY | 21157 | | | | | nonmetro county (rural) | manufacturing-dependent | https://maps.google.com/?q=MarshallCounty+KY |
| | Martin County | KY | 21159 | | | | | nonmetro county (rural) | mining-dependent | https://maps.google.com/?q=MartinCounty+KY |
| | Mason County | KY | 21161 | | | | | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=MasonCounty+Kentucky |
| | McCracken County | KY | 21145 | | Paducah, KY-IL 37140 | Paducah-Mayfield, KY-IL 424 | Central | nonmetro county (rural) | nonspecialized | https://maps.google.com/?q=McCrackenCounty+KY |
| | McCreary County | KY | 21147 | | | | | nonmetro county (rural) | federal/state
government-dependent | https://maps.google.com/?q=McCrearyCounty+KY |